Author(s): Anand Betdur1, Ashwath S. V2, Neelam V3, Siddhant Bansal4, Shashidharan Basappaji5
To study the clinical profile of coronary artery disease in women and to identify the influence of the risk factors.
We conducted a prospective observational study in Vydehi Institute of Medical Science and Research Centre (VIMS & RC), Bengaluru during the period June 2012 to Dec 2013. Patients admitted with history suggestive of coronary artery disease were evaluated clinically and investigated for risk factors. Prognosis with regards to morbidity and mortality following the standard treatment protocol was documented.
Out of 100 cases of coronary artery disease (CAD), 32 had Acute Myocardial infarction (AMI), 23 with Unstable Angina and 45 patients had Stable Angina. Nearly half of the patients had the traditional risk factors, namely hypertension (HTN), diabetes mellitus (DM), hyperlipidaemia and obesity. Chest pain was the most common symptom. Mortality was 14% which was observed predominantly in post-menopausal women who presented after 24 hours of the onset of symptoms.
Coronary artery disease is no longer a disease of men. Men and women share the same traditional risk factors like HTN, DM, Obesity, and Hyperlipidaemia. Increased incidence of complications and mortality occurred in those who presented after 24 hours of the symptoms. Our study highlights the importance of early recognition of CAD and initiation of thrombolytic therapy, to reduce significant morbidity and mortality.