Clinical and Metabolic Profiles of Patients with Lean Non-Alcoholic Fatty Liver Diseases (NAFLD) Attending a Tertiary Health Care Centre of North-Eastern Region

Abstract

Dr. Swapan Kumar Das

Corresponding Author:Corresponding Author:Dr. Swapan Kumar Das,Assistant Professor, Department of General Medicine,Agartala Government Medical College and GBPH, Kunjaban, Agartala- 799006,Tripura.E-mail: drskrdas@gmail.comDOI: 10.18410/jebmh/2019/670 ABSTRACTBACKGROUNDNAFLD has become one of the most common liver conditions throughout the world which is now increasingly diagnosed in developing countries. Most of Lean NAFLD Patients are prone to Metabolic Syndrome. METHODSIn this cross-sectional study descriptive and inferential statistical analysis has been carried out taking 75 (seventy-five) cases of lean NAFLD from January 2016 to June 2017 at Agartala Government Medical College & G.B.P. Hospital. RESULTSAmongst 75 (seventy-five) cases, 40% patients had systolic BP in the range of 120-139 mmHg followed by 36% below 120 mmHg and 18% had SBP >140 mmHg. Diastolic BP in the range of 80-89 mmHg was found in 64% of patients. Out of the 22 hypertensive patients, 18 were from 45-60 years age group, whereas most of the normotensive patients belongs to 30-45 years age group. Out of 20 diabetes patients, 14 were from 45-60 years age group, whereas most of the non-diabetes patients belongs to 30-45 years age group. In <30 years total cholesterol was 179.00 ± 29.70 mg/dL, 179.32 ± 24.90 mg/dL in 30-45 yrs. and in 45-60 yrs. was 194.55 ± 25.84 mg/dL. Triglyceride level was 140.00 ± 0.00 mg/dL in <30 years, 175.34 ± 43.87 mg/dL in 30-45 yrs. and 243.07 ± 79.24 mg/dL in 45-60 yrs. Waist hip ratio was raised in 61.3% patients, while 38.7% patient had normal waist-hip ratio (WHR). 20 patients from the age group 45-60 years had metabolic syndrome among 33 positive cases. It was followed by 13 patients from 30-45 years age group, whereas no patients belong to <30 years age group. 80% of the patients had low HDL level, 74.7% patients had hypertriglyceridaemia and all of them had metabolic syndrome too. CONCLUSIONS44% of the cases had metabolic syndrome and 80% of them had at least one component of metabolic syndrome. The lean NAFLD patients were metabolically similar to obese population.

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