Madhu Babu Chekuri1, Padmaja Pinjala 2, Rajeev Singh Thakur 3, N. Srinivas4
Cutaneous tuberculosis is a chronic disease caused by Mycobacterium tuberculosis. It is primarily a granulomatous disease. We studied the clinical pathological profile of 42 cases of cutaneous tuberculosis in Osmania General Hospital from December 2010 – October 2012.
A total of 42 cases of cutaneous tuberculosis attending DVL OPD at Osmania General Hospital were studied along with clinical features, age, sex, duration of illness in correlation with Mantoux test and types of cutaneous lesions.
Out of 42 cases, commonest variant was Lupus vulgaris (38.06%). Majority (37.5%) of the cases were in the age group of 21-30 years. Male preponderance was noted in the study with highest incidence in the low socioeconomic group. The location of cutaneous tuberculosis was high in head and neck region (23.80%) and clinically majority of cases were (38.06%) found to be Lupus vulgaris variant.
Among the various types of cutaneous tuberculosis, Lupus vulgaris is the commonest variant followed by scrofuloderma in the study population. The other variants like Tuberculosis verrucosa cutis accounted to 19.04% of the study cases. A small percentage were contributed by Lichen scrofulosorum (2.38%) and Papulonecrotic tuberculids (2.38%) respectively. Lupus vulgaris was the most common histopathological variant. Most of the components of cutaneous tuberculosis on histopathology exhibited hyperkeratosis, hyperplasia, pseudoepitheliomatous changes; lymphocytic dermal infiltrate, epithelioid cell granulomas in the dermis, vasculitis changes in the dermis with changes of septal or lobular panniculitis.