CARDIOMETABOLIC PROFILE IN PATIENTS OF ACUTE CORONARY SYNDROME

Abstract

Saish Pradip Alegaonkar

BACKGROUND
The aim is to study cardiometabolic profile in patients with acute coronary syndrome (ACS) with reference to metabolic
syndrome (MS).
MATERIALS AND METHODS
This study was carried out in Acharya Vinoba Bhave Rural Hospital of Jawaharlal Nehru Medical College, Sawangi (Meghe),
Wardha from September 2014 to August 2016. A total of 200 diagnosed patients of ACS admitted in medicine intensive care
unit were enrolled in study and investigated for serum fasting blood sugar (FBS), serum high density lipoprotein (HDL), serum
triglyceride (TG) and serum C- reactive protein (CRP). Anthropometric measures like height, weight, body mass index (BMI)
and waist circumference (WC) were calculated.
RESULTS
Mean age of males in study subject was 55.26 ± 13.05 and in females 60.25 ± 12.82. BMI and WC were significantly higher
in males than females (p - <0.0001). Percentage of MS was higher in males than females (p – 0.009). Of the total study
population, 16 (11.27%) males and 16 (8%) females had metabolically obese normal weight (MONW). BMI, WC, HDL value
had significant differences in all 3 presentations of ACS. DM and HTN were more common in MS than NMS. BMI, WC, FBS and
TG values were higher in MS than non-metabolic syndrome (NMS). HDL values were lower in both genders with MS than NMS.
CONCLUSION
We conclude that ACS is a major burden of public health. MS is a key association with ACS. Appropriate preventive strategies
focusing on population in general and high risk groups should be undertaken aggressively. More population based studies
encompassing subgroups like “MONW” should be done that may throw more light on evidence based practice to prevent
future cardiovascular diseases (CVD).

image