Rema Priyadarsini1, Saju P. R2, Akhil R. Nambiar3, Santha Sadasivan4
Adenocarcinoma of prostate is the most common form of cancer in men accounting for 29% of cancers in developed nations and the incidence of prostatic cancer is 6.4% in males of Trivandrum District.
MATERIALS AND METHODS
All prostatic biopsies taken per rectally and stained by haematoxylin and eosin. In suspected cases of malignancy immunohistochemical markers, the AMACR P504S and high molecular weight cytokeratin 34E12 were done.
The total number of cases studied were 142. The final diagnosis with histomorphological features show that maximum cases were prostatic carcinoma constituting 45.5% of the samples received.
All prostatic carcinomas were graded by revised Gleason’s grade (ISUP 2005) and the use of immunohistochemical markers in arriving at a definite diagnosis in carcinoma prostate was confirmed.