C - REACTIVE PROTEIN (CRP) AS A DIAGNOSTIC PARAMETER IN ACUTE APPENDICITIS ??? A DOUBLE BLIND STUDY

Abstract

Chaitra S1

ABSTRACT: BACKGROUND AND OBJECTIVES: Acute appendicitis is one of the most common causes of right iliac fossa pain and one of the most common cause of surgical emergencies. The clinical trial of history compatible with acute appendicitis, pain at McBurney???s point and leucocytosis has diagnostic accuracy rate of less than 80%.Hence high rate of about 15-30% of negative explorations for acute appendicitis is unacceptable is today???s era of evidence based medicine. So the objective of the study was to evaluate the role of accuracy of CRP measurement in the diagnosis of acute appendicitis and to reduce morbidity by avoiding negative explorations. METHODS: The present study was conducted in 50 patients at the department of Surgery, MMC & RI, Mysore have been clinically diagnosed by surgeons as having acute appendicitis and posted for emergency appendicectomy. Preoperatively blood was sent for CRP estimation, (more than 10,000 per mm 3) after operation all specimens were sent for HPE examination; results of CRP were correlated with HPE reports to evaluate their role in diagnosis of acute appendicitis.
 

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