Abu Lais Mustaque Ahmed1
In an attempt to observe the haemodynamic parameters in the perioperative period by treating newly detected patients of hypertension (Grade 1 and Grade 2, JNC VII) with two doses of oral atenolol, this study has been taken up in Assam Medical College and Hospital, Dibrugarh, in an endeavour to determine and compare the efficacy of such pre-treatment against placebo and also to determine the adverse effects encountered.
METHODS & MATERIALS
This randomised placebo controlled study was conducted in Assam Medical College & Hospital, Dibrugarh from July 2005 to June 2006, under the Department of Anaesthesiology and Critical Care, with prior permission from the hospital authorities after fulfilling all the norms and after taking informed consent from all patients included in this study.
The results of the present study reconfirm the fact that altered haemodynamics in the perioperative period; particularly the heart rate can be effectively kept within the normal range with the use of oral beta blocking drugs like atenolol.
Considering the above facts, it can be concluded that long-acting beta blockers like atenolol can be used effectively to prevent tachycardia and its deleterious effects like myocardial ischaemia and various forms of arrhythmias in the perioperative period can be reduced effectively. In presence of intensive monitoring facilities, unnecessary cancellation of cases can be avoided and hence reduction in hospital stay and cost of treatment can be achieved safely.