ASPARTATE TRANSAMINASE - IS IT USEFUL AS A BIOCHEMICAL MARKER AND AS A PREDICTOR OF SEVERITY OF PREGNANCY-INDUCED HYPERTENSION AND ITS COMPLICATION

Abstract

Rupinder Kaur1, Ramesh Sonowal2

OBJECTIVES
To compare serum Aspartate Transaminase of normotensive pregnant women with those of pre-eclamptic and eclamptic women. To determine the relationship of levels of serum Aspartate Transaminase with severity of pregnancy-induced hypertension and its complications.
METHOD
The study was carried out on pregnant hypertensive patients attending Outpatient Department of Obstetrics and Gynaecology Department, AMCH Dibrugarh, Assam from 1st July 2013 to 30th June 2014. Normotensive pregnant women were taken as controls. Each serum sample from the control group as well as study group was estimated for Aspartate Transaminase using standard methods, and a comparison is drawn and analysed using t-test and chi-square test.
RESULTS
Serum Aspartate Transaminase levels were high in the study group. The levels of this enzyme were normal in the control group.
CONCLUSION
Aspartate Transaminase levels in patients suffering from preeclampsia and its complications are consistently higher compared to the normotensive pregnant patients. To determine the usefulness of inclusion of this enzyme along with other cardiac enzymes in the panel of investigations of pregnant women universally needs further large scale comparative studies.

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