Antiviral, Anaesthetic and Antipyretic Drugs in the Management of Herpes Labialis


Karishma Desai and Jayanth Kumar*


Herpes labialis, commonly known as cold sores, is a type of infection by the herpes simplex virus that affects primarily the lips. Symptoms typically include a burning pain followed by small blisters or sores. The first attack may also be accompanied by fever, sore throat, and enlarged lymph nodes.


The main aim of this study was to evaluate the antiviral, anaesthetic and antipyretic drugs used in the management of Herpes labialis.

Materials and method

The study was undertaken in a university setting. The data was collected from June 2019 - Feb 2021 cases out of which only 110 patients with Herpes labialis were included for the study. Data was statistically analysed using SPSS and frequency analysis followed by chi square analysis was done which is used to compare and correlate the data with the distribution.


A total of 110 patients were included. About 52.29 % are males and 47.71 % are females. The topical antiviral acyclovir was used by 92.66 % of people and systemic antiviral acyclovir is used by 51.38 %, the topical anaesthetic lidocaine gel was used by 44.95 % of people, systemic antipyretic paracetamol was used by 50.46 %.


This study with all the limitations concludes that the topical antivirals were used in the majority of the patients along with systemic antipyretic. Topical anaesthetics were not used commonly in Herpes labialis as pain is not a common presenting complaint.