Debabrata Dutta1, Manab Jyoti Gohain2
Basic liver function test is a part of preoperative evaluation of biliary lithiasis. It is seen in many worldwide reports about significant alterations of liver function both in pre and post-operative period. As a unique geographical placement and different dietary habit adopted by North East Indian population, this present study will stress upon the significance of alteration of liver function in biliary lithiasis cases.
MATERIALS AND METHODS
A total of 400 patients of extrahepatic biliary lithiasis, subjected to either open or laparoscopic procedure, are prospectively analysed by examining LFTs pre-operatively, the 1st day after surgery and on completion of 4 weeks in a tertiary teaching hospital of North East India.
Alteration in AST, ALT, GGT were seen with minor changes in serum bilirubin and proteins on 1st post-operative day noticed in two-third of the patients. After 4 weeks, these tests came down to almost their normal values.
Though mild-to-moderate alterations of LFTs are seen during initial period, after 4 weeks, values came to their base level.