Subrata Choudhury, Vishwa Prakash Das, Sudip Barua, Amit Kumar Ghosh
Diabetic neuropathy is one of the most important complications of type 2 diabetes mellitus. But whether the glycaemic variability is related with the diabetic neuropathy is not proven with sufficient data yet. So, this study is aimed at determining the association between the glycaemic variability with the diabetic neuropathy. Fifty patients (32 males and 18 females; aged (yr) 58.32 ± 9.629 (mean ± SD)) were investigated for this study. Glycaemic variability is estimated by HbA1c measurement and neuropathy is quantitatively evaluated by Nerve Conduction Velocity (NCV) of median nerve for sensory and motor component. HbA1c had a significant association with the NCV. In patients in whom HbA1c value improves both right and left sided motor and sensory NCV increased which is statistically significant (P?0.05). In patients in whom HbA1c value deteriorates both sided median nerve motor and sensory NCV decreased, but the left sided reduction in NCV is statistically significant (P?0.05) but in right side reduction in motor and sensory NCV is statistically insignificant (P?0.05). So, we may conclude that glycaemic variability could be a risk factor. This study addresses one of the key issues related to the evaluation of diabetic neuropathy.
