Siva Subramanyam S1, Ramesh Basavaiah2
Stroke is the leading cause of disability worldwide, the second most common cause of dementia and the third leading cause of death. It is unclear whether serum uric acid promotes or protects against the cerebrovascular disease. Hence, a search for other risk factors is the need of the hour. The aim of the study is to study the role of serum uric acid, serum calcium and serum albumin in acute ischaemic stroke and its effect on stroke outcome.
MATERIALS AND METHODS
A cross-sectional study was carried out in ESIC Medical College and PGIMSR, Rajajinagar, Bengaluru, over a period of 18 months in 100 cases of who met the inclusion criteria were studied. Patients presenting within 72 hours of onset and aged ≥40 years were included in this study. Apart from routine investigations, serum albumin, calcium and uric acid levels were done in all patients.
Out of 100 patients, 63% were males and 37% were females. Ratio was 1.7:1. Majority of stroke population are between 50 to 69 years. Hypertension constitutes the major risk factor in this population as 79% of population is hypertensive. Serum calcium, albumin and uric acid values had a highly significant correlation with neurological severity by NIHSS scores (p<0.001) and with the short-term outcome by Barthel index (p<0.001).
Serum albumin, serum calcium and serum uric acid values can predict initial neurologic severity and short-term outcome in AIS.