Ritu Saloi, Gokul Chandra Das
Infertility affects large number of couples both globally as well as in India. Primary infertility is a common, preventable, but neglected reproductive health problem in developing countries like India. The present study was undertaken in an attempt to find out the role of hyperprolactinaemia or elevated prolactin level in the development of primary infertility in female and analyse its effect in folliculogenesis.
MATERIALS AND METHODS
In this study, 52 female subjects with the complaint of primary infertility in the child bearing age group who have attended Obstetrics and Gynaecology, Outpatient Department, Gauhati Medical College and Hospital, Guwahati, for treatment were taken as the cases.
The incidence of hyperprolactinaemia, i.e. serum prolactin levels >25 ng/mL in the infertile women was 42.31%, whereas in the control group of fertile females, the incidence of hyperprolactinaemia was 13.46%. Anovulatory cycles were detected in 51.92% of the infertile group, whereas in the control group, it was detected in 7.69%. Galactorrhea was present in 9.62% of the infertile women. Menstrual disorders observed in the infertile and control groups were 61.54% and 17.31%, respectively. The results of the study were statistically analysed.
There is a high incidence of hyperprolactinaemia in infertile women. Percentage of anovulatory/delayed ovulatory cycles were also found to be higher in the infertile group than the fertile females