Abstract

A STUDY ON SEROPREVALENCE OF DENGUE IGM ANTIBODY IN SUSPECTED CASE OF DENGUE FEVER IN AND AROUND JAMNAGAR, GUJARAT (INDIA)

Author(s): Saurabh Chhotalal Gamit1, Hitesh Kantilal Shingala2, Mala Sinha3

BACKGROUND
Dengue virus belongs to family Flaviviridae, it spread by the bite of infected Aedes mosquitoes. It breeds in fresh water. It causes a wide spectrum of illness from mild illness to severe fatal Dengue Haemorrhagic Fever/Dengue Shock Syndrome (DHF/DSS).
The aim of the study is to find out seroprevalence of dengue IgM in and around Jamnagar by presence of virus specific dengue IgM antibody from serum samples taken from suspected dengue patients.
MATERIALS AND METHODS
This is retrospective study conducted at tertiary care hospital, Jamnagar. Patient with history of dengue fever more than 5 days were included in the study. Serum samples were screened for dengue IgM by ELISA method. Study was conducted in our institute from July 2016 to June 2017. Total 1202 serum samples of suspected patient of dengue IgM by ELISA method.
RESULTS
Out of 1202 samples, total 254 (21.13%) were positive for dengue IgM Ab among this- 177 (69.69%) male and 77 (30.31%) female and 78 (30.71%) were 0-20 of age, 131 (51.57%) were 20-40 of age and 45 (17.72%) were 40 of age. 175 (82.28%) positive cases between October to December in post-monsoon season.
CONCLUSION
Study shows that prevalence of dengue fever is more in post-monsoon season, more common in middle age group and in male than female, so early diagnosis is very important to reduce mortality rate.
KEYWORDS
Dengue, Seroprevalence, Jamnagar, ELISA, IgM, P-Value, Post Monsoon.