A STUDY ON ESTIMATION OF SERUM CALCIUM IN SUBCLINICAL HYPOTHYROID FEMALES OF DIFFERENT AGE GROUPS AND ITS CORRELATION WITH THYROID STIMULATING HORMONE (TSH)

Abstract

M. Kaleemullah Khan 1 , Mohd. Nasir Mohiuddin 2 , Nooruddin Owaisi

BACKGROUND Hypothyroidism is a clinical condition arising because of the inadequacy of thyroid hormones or from inability to perform a normal function. Hypothyroidism is a typical metabolic condition in almost all community groups. In India, 42 million individuals are experiencing thyroid disease; hypothyroidism being the commonest thyroid disorder.(1) Serum calcium levels are lower in patients with high TSH than with typical TSH (p <0.01).(2) METHODOLOGY There were 50 females with SCH were selected in the study. Patients with 18 to 65 years of age, with TSH levels more than 5.0 mIU/L, free T4 within normal limits, and general well-being patients were incorporated. The study period was from January to April 2016. Owaisi Hospital and Research Centre, it is a 1000 bedded hospital with super specialty services in Hyderabad, giving particularly tertiary level human services to all strata of individuals. RESULTS Out of 50 patients, 24 patients with hypothyroidism are in hypocalcaemia, which constitute 48% (n=24) of the people required in the study had estimation of serum calcium under 9 mg/dL. This shows to be the one of the important concern associated with hypothyroidism. In rest 52% (n=26) of patients who were having normal calcium levels, chances of developing hypocalcaemia in future is high. DISCUSSION The mean age, serum calcium and thyroid stimulating hormone (TSH) in AlaEldin S. Ashmaik et al was: Age: 32.00±15.76, TSH: 26.02±34.74, and serum calcium: 7.97±.62 while in our study it shows a mean age of 39.9 ±13.82, TSH: 10.47 ±3.46, and serum calcium: 9.04 ±1.47. The mean age in our study was higher than the study by AlaEldin done in Sudan population, the mean TSH was found to be much lower while the serum calcium levels show elevated levels in our study in contrast to study by AlaEldin S. Ashmaik et al. CONCLUSION This study presumed that in Telangana state, patients have low levels of serum calcium in hypothyroidism. S.Ca++ in hypothyroid people demonstrates a constructive connection between the S.Ca++ and serum TSH. These fluctuations of serum calcium ought to be considered in treating the patients with hypothyroidism by therapeutic experts.

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