Shwetha B. R1, Saraswathi Subramanian2, Prashant V. Solanke3
With regard to normal labour, many eminent obstetricians have aptly remarked that of all the journeys the most dangerous is the very first one we make through the last ten centimetres of the birth canal. Hence, it is imperative that this short but crucial process is made safest for the baby. The role of a good obstetrician is to convert an abnormal situation where the events are not happening to one in which order is regained. Methods that aim at minimizing the incidence of functional cervical dystocia and cutting short the 1st stage of labour are always accepted by the obstetricians and patients.
To compare the effect of Inj. Buscopan IV and Inj. Drotaverine & to find out which of the above drugs is more effective in shortening the labour.
This study was undertaken at Sree Mookambika Institute of Medical Sciences from June 2015 to December 2015. The sample size was calculated using the formula sample size n=2Z12S2/d2., sample size required is 29. We have taken 50 sample sizes per group. This is a cross-sectional study. Inclusion criteria was primigravidae with full term gestation with vertex presentation in active labour.
The mean duration of 1st stage (active phase) of labour in group D was 118.04 mins., that of group H 129.74 mins. and of group C 185.38 mins. The mean duration of 2nd stage of labour in group D was 23.20 mins., that of group H 25.38 mins. and of group C 23.97 mins. The mean duration of 3rd stage of labour in group D was 11.44 mins., that of group H 14.02 mins. and of group C 15.16 mins. Rate of cervical dilatation is significantly more in Group D when compared to Group C (3.147 mins. vs. 1.97 mins.) (p<0.001). The rate of cervical dilatation is significantly more in Group H when compared to Group C (2.78 mins. vs. 1.97 mins.) (p<0.001). Rate of cervical dilatation was also significantly more in Group D when compared to Group H (3.147 mins. vs. 2.78 mins.) (p<0.001). Frequency of usage of higher number of doses is significantly more in Group D compared to Group H with p<0.001. There was no significant difference in the Apgar score at 1 min. and 5 mins., birth weight and NICU admissions among the three groups.
There is a distinct advantage in using drotaverine hydrochloride as an antispasmodic of choice for effectively shortening the first stage of labour. It re-establishes the pivotal role of drotaverine hydrochloride in the acceleration of the first stage of labour. It is also reassuring that neither of the drugs used were associated with any untoward maternal or foetal effects while accelerating the first stage of labour.