A STUDY OF LOCALLY ADVANCED CARCINOMA OF BREAST

Abstract

Prabhakar Jenna1, Sushma Jagadev2

BACKGROUND
Worldwide, breast cancer is the most frequent cancer in women and represents the second leading cause of cancer death among women. Locally advanced breast cancer constitutes more than 50-70% of the patients presenting for treatment has two common problems in treatment. Achieving local control and prolonging survival by preventing or delaying distant metastasis. Today, treatment of LABC requires a combination of systemic and local/regional therapies. The aim of the study is to study the clinicopathological presentation, age distribution and various modes of management of locally advanced breast carcinoma. Worldwide breast cancer is the most frequent cancer in women and represents the second leading cause of cancer death among women. Locally advanced breast cancer constitutes more than 50-70% of the patients presenting treatment. MATERIALS AND METHODS
The present study includes 50 patients who attended Department of General Surgery for a period of three years.
RESULTS
The patients were regularly followed up and at the end of the study 35 (70%) of the patients were doing well. 4(8%) of the patients developed distant metastasis and 3 (6%) of the patients developing local recurrence. 8 (16%) of the patients were lost follow up.
CONCLUSION
About half of the cases presenting with breast cancer are in locally advanced stages. Multimodality therapy is the effective treatment of locally advanced carcinoma of breast. Breast cancer management is a challenge and improvement in therapies are needed for disease-free interval and overall survival period.

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