A STUDY OF IMPAIRED GLUCOSE TOLERANCE TEST IN PULMONARY TUBERCULOSIS

Abstract

Devpriya Lakra1 M. K. Minj2 Rashmi Dewangan3 S. P. Kujur4 R. C. Arya5 A. K. Bhardwaj

The link between Diabetes mellitus & Tuberculosis has been recognizing for centuries. Recently Tuberculosis has re-emerged as a major health concern. There is growing evidence that Diabetes mellitus with Tuberculosis may affect disease presentation and treatment. The Tuberculosis also influences glucose intolerance and influences the glycaemic control in the people with Diabetes mellitus. Approximately 2 Million persons worldwide died of Tuberculosis and 9 Million become infected each year. (CDC, 2007)1 . With the convergence of tuberculosis and diabetes Mellitus epidemic, co-affliction with the two diseases is on the rise. The observational study was conducted with 100 patients. The patients with Pulmonary Tuberculosis sputum positive/negative with radiological lesions was admitted in medicine wards of our hospital between years 2009-2011. The aim of our study is to find out the prevalence of GTT in patients of Pulmonary Tuberculosis Age, sex distribution of impaired Glucose Tolerance Test (GTT) in Patients with pulmonary tuberculosis and study the correlation between impaired GTT with Sputum positivity and also radiological extent of disease. The patients were subjected to oral GTT and results were evaluated according to the WHO criteria and the statistical analysis was done to determine the P value and significance on the basis Chi-square test. The results found in the studied patient were that prevalence of abnormal GTT in Pulmonary Tuberculosis patients was found to be 22% (P=0.07). Abnormal GTT was more common in males as compared to females and this was found to be significant (P=0.692). Sputum positive Pulmonary Tuberculosis is strongly associated in patients with abnormal GTT (P=0.03), and bilateral lung involvement was more common among Pulmonary Tuberculosis patients with abnormal GTT

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