A STUDY OF EFFICACY OF PROSTAGLANDIN ANALOGUES IN COMPARISON WITH TIMOLOL MALEATE AS FIRST DRUG OF CHOICE IN THE TREATMENT OF PRIMARY OPEN-ANGLE GLAUCOMA

Abstract

Namboori Padmavathi, Venkateshwara Prasad Padala

BACKGROUND Glaucoma is an ischaemic optic neuropathy comprising of three entities; one is raised intraocular pressure, second one is optic disc changes and third one is visual field defects. Intraocular pressure remains the major modifiable risk factor. The aim of the treatment is to lower the IOP and thereby prevent the significant functional visual defect and preserve the visual function. MATERIALS AND METHODS The current study is a prospective hospital-based observational study conducted over a period of two years in a sample of 50 patients attending the Outpatient Department, Department of Ophthalmology, Rangaraya Medical College, Government General Hospital, Kakinada, Andhra Pradesh. RESULTS A study of efficacy of prostaglandin analogues in comparison with timolol maleate as first drug of choice in the treatment of primary open-angle glaucoma. CONCLUSION According to the study, prostaglandin analogues showed higher efficacy in reducing the intraocular pressure as compared to that of the timolol maleate.

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