A STUDY OF DIASTOLIC DYSFUNCTION IN PATIENTS OF TYPE-2 DIABETES MELLITUS IN RURAL POPULATION OF WESTERN UTTAR PRADESH

Abstract

Manoj Kumar

BACKGROUND
Diabetes mellitus is a disease with multisystem involvement. Most common cardiovascular complications of diabetes mellitus is the presence of diabetic cardiomyopathy. Diastolic left ventricular dysfunction may be early sign of diabetic cardiomyopathy, which is easily accessed by echocardiography.
The aim of the study is to study the prevalence of left ventricular diastolic dysfunction (LVDD) in asymptomatic, non-hypertensive patients of diabetes mellitus.
MATERIALS AND METHODS
A study was carried out on 110 diabetic patients. All the patients were subjected to detailed history, physical examination and specific investigations were done to find out the prevalence of diastolic dysfunction.
RESULTS
Diastolic dysfunction was present in 79.10% of patients. Diastolic dysfunction was present more in female than male (52.88% vs. 47.12%). Grade 1 diastolic dysfunction was the commonest form of diastolic dysfunction followed by grade 2 and grade 3. Diastolic dysfunction was positively correlated with HbA1c level (r=0.191, p=0.046), duration of diabetes (p-value <0.05, r=0.651) and advancing age (r=0.505, p<0.05).
CONCLUSION
Echocardiography is a sensitive method to investigate for diastolic dysfunction. There is a high prevalence of diastolic dysfunction in diabetes, which is an early marker of diabetic cardiomyopathy.

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