A STUDY OF 100 PATIENTS OF TYPE 2 DIABETES MELLITUS IN RELATION WITH CAROTID ARTERY INTIMA MEDIA THICKNESS AND DYSLIPIDAEMIA

Abstract

Surya Prakasa Rao Salla1, Ramprasad Kadiyala2, Srikanth Gummadi3, Suma Pusapati4, Yaswanth Roy Chowdary Alapati5

BACKGROUND
The Framingham study pointed out that diabetic individuals have dyslipidaemia and hypertension, obesity are more prone to metabolic syndrome and its sequelae namely coronary artery disease (CAD), cerebrovascular disease and vascular atherosclerosis.1 Carotid intima media thickness (CIMT) is a relatively simple, non-invasive measurement that uses ultrasound to detect the presence of an extent of atherosclerosis. Normal CIMT is 0.9 mm.
Aims and Objectives:
1. To evaluate the carotid intima media thickness in 100 patients of type 2 diabetes mellitus with its duration, hypertension, age and sex distribution and also lipid profile abnormalities.
2. To study the correlation of carotid intima media thickness with dyslipidaemia.
MATERIALS AND METHODS
100 patients of type 2 diabetes mellitus getting admitted into medical wards of Anil Neerukonda Hospital of NRI Institute of Medical Sciences, Sangivalasa, Visakhapatnam District of Andhra Pradesh. The patients were divided into two groups based on CIMT thickness, group 1 with CIMT < 0.9 and group 2 with CIMT ≥ 0.9. The purpose of the study was to study the carotid intima media thickness in patients with type 2 diabetes mellitus and to correlate with lipid profile.
RESULTS
An observation was made in this study that of the 47 patients who had atherosclerosis risk factors like diabetes mellitus, majority (74.4%) had intima media thickness greater than 0.9 mm. At the same time, of the 53 patients who had only risk factors for atherosclerosis but no events, majority (60.3%) had IMT less than or equal to 0.9 mm.
CONCLUSION
The present study revealed that the CIMT in diabetic patients with atherosclerotic events was significantly higher as compared to carotid artery IMT in diabetic patients who had only risk factors for atherosclerosis, but no events with a P value < 0.01.

image