A RETROSPECTIVE STUDY OF INCIDENCE, CLINICAL PRESENTATION AND TREATMENT OUTCOME OF ORGANOPHOSPHORUS POISONING IN KONASEEMA REGION OF ANDHRA PRADESH

Abstract

Joginaidu Mula1, Narasimha Raju A. V2, Anand Acharya3

BACKGROUND
Organophosphorus compounds are highly toxic to human and it is easily available. So suicidal, homicidal and accidental poisoning incidence has increased in these 4 to 5 decades. Toxic effects of these compounds are associated with significant morbidity and mortality. Their ease of access and sociocultural factors play important role in selecting them as a self-poison.
MATERIAL AND METHOD
Present study is a hospital based retrospective study conducted during June 2013 to Dec 2016 in the Dept. of General Medicine, Konaseema Institute of Medical Science, Amalapuram.
RESULT
During three and half years of study, sixty two patients were admitted with organophosphorus poisoning. Out of them, 36 were between 15 to 45 years of age and 6 were below 15 years of age. Male patients were more than female, that is 46 and 16. Most of the patients were from rural area that is fifty out of sixty two. Pulmonary oedema was the common complication that is 16. Respiratory failure and aspiration pneumonia was present in 12 and 10 patients respectively. Eight patients presented with intermediate syndrome. Two patients developed neurological complication.
DISCUSSION AND CONCLUSION
Respiratory complication was the most common presentation that is in the form of pulmonary oedema, respiratory failure and aspiration pneumonia; that is 25%, 19% and 16% respectively, which is similar to the study of other authors, intermediate syndrome was also present in 12.90% of cases. Easy availability of this insecticide is another problem. Educating the people and strong regulatory condition is required to decrease the incidence.

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