A RATIONAL PHARMACOTHERAPEUTIC STUDY IN PHARMACOVIGILANCE: A COMPARATIVE ASSESSMENT OF SAFETY BETWEEN TOPICAL 1% NADIFLOXACIN AND 0.1% ADAPALENE COMBINATION THERAPY AND TOPICAL 1% NADIFLOXACIN AND 0.025% TRETINOIN COMBINATION THERAPY, IN MILD TO MODERATE ACNE, IN TERTIARY CARE HOSPITALS, IN INDIA