Chitra Kumbasubramaniyan1, Shanthi Chandran2, Vittal Shankreppa3
Factor V Leiden mutation (Factor V Leiden) is an autosomal dominant haemostatic disorder that predisposes affected persons to venous thromboembolic events (VTE). Although the mutation causing FVL is easily diagnosed using molecular DNA techniques,(1) patients who are heterozygous for this disorder often remain asymptomatic until they develop a concurrent prothrombotic condition. Pregnancy, which may increase an individual woman’s risk of venous thromboembolic events by 5- to 6-fold.(2) Because there are potentially serious effects of FVL for both the mother and the child, and availability of effective treatment strategies, early detection and treatment of this condition is warranted.(3) We are presenting this case in order to emphasise the existence of Factor V Leiden in Indian population and its approach during pregnancy.