Ateeq Akbar Mohammed1, A. V. Narsimha Raju2, K. S. R. Swami3
BACKGROUND
Diabetes mellitus is a chronic metabolic disorder and complications are due to persistent hyperglycaemia. So to prevent or delay the complication, near-euglycaemia needs to be achieved. For that various drugs are used.
MATERIAL AND METHODS
This is a prospective, randomised open labelled study conducted in the Department of General Medicine, Amalapuram. Various parameters were measured before and after 16 weeks of study like FPG, PPPG, HbA1c, LDL, TG, and total cholesterol.
RESULTS
There was decrease in all the parameters in both the groups, but c-peptide level was decreased more in group B than group A and also increase in HDL concentration was more in group B.
CONCLUSION
When one antidiabetic drug is not sufficient to maintain euglycaemia and to prevent complication, various combinations are used. So various drug combinations to be evaluated and study to be conducted to establish the efficacy and more therapeutic options.
