Abstract

A PROSPECTIVE STUDY OF DYSLIPIDAEMIA AND OBESITY IN HYPERTENSION PATIENTS

Author(s): Ponnana Raja Kumar, Siripurapu Sasikala

BACKGROUND The association of hypertension and dyslipidaemia is common and been proved by various studies beyond doubt, the reason for this co occurrence has not been probed out yet. Three possible mechanisms are proposed for this but none have been proven. 1. Dyslipid a emia can increase the incidence of h ypertension. 2. Hypertension can increase the incidence of d yslipid a emia. 3. There may be a common factor which cause increased incidence of both. MATERIALS AND METHODS Patients who are diagnosed as hypertensive s tudy population included patients attending Medicine OPD of Konaseema Study period is from February 2015 to October 2017. The s tudy design is c ross sectional study with cases and controls. This study is conducted to assess the abnormalities in plasma lipi d profile of hypertensive patients and to determine the factors influencing it. Present study is designed to study the prevalence and pattern of lipid profile abnormalities in newly diagnosed hypertensive patients. To study the influence of various clinica l, demographic, social and socioeconomic parameters on lipid profile abnormalities in hypertensive patients. RESULT S The total cholesterol, triglycerides, LDL C and HDL C are significantly higher in hypertensive patients (cases) when compared with non hypertensive patients (control). Significant percentage of dyslipidaemias is present with respect to total cholesterol and triglycerides when compared with groups with lowest lipid values. Significantly higher percentages of prediabetic hypertensive patients have their total cholesterol and LDL cholesterol in dyslipidaemia range when compared with non diabetic hypertensive patients. CONCUSSION Hypertensive patients have significantly higher levels of all forms of cholesterol and higher percentage of individuals in dyslipid a emic state when compared with normotensive persons. Hypertensive females have significantly higher levels of HDL C when compared to hypertensive males. Elderly hypertensives have significantly high total cholesterol values when compared with young and middle aged hypertensives. Smoking have a significant impact on the lipid profile of hypertensive obesity