A NON-RANDOMISED PROSPECTIVE STUDY OF THYROID ORBITOPATHY IN A TERTIARY CARE CENTRE

Abstract

Siddharth Karan1, Manisha Nathani2, M. Tanveer Ali Khan3, Aftab Abdul Khader4, Suchetha Ireni5, Abdul Basith Syed6

Graves’ disease is an autoimmune condition where TSH receptors are targeted by the auto-antibodies. Although most patients have clinical or laboratory evidence, the disease process can occur even in the absence of detectable thyroid abnormality. Although most cases of TAO can be managed medically without any visual loss, it may result in exposure keratitis and compressive optic neuropathy. There was female preponderance noted. Maximum number of patients were in the 25-50 years of age group. More than 65% of the patients were hyperthyroid followed by euthyroid in 25% and then hypothyroid in less than ten percent. In both the sexes, the hyperthyroid status was the most common followed by euthyroid and hypothyroid. No male was reported to be hypothyroid. The most common presentation was found to be bilateral than unilateral. Inferior rectus was the commonest muscle involved followed by medial rectus, superior rectus-LPS complex and lateral rectus in descending order. Incidence and various modes of presentation of ‘Thyroid Orbitopathy’ of our study at our tertiary centre in Hyderabad are correlating with national and international studies.

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