Noushad Thekke Puthiyotti1, Jayakumar Edathedathe Krishnan2, Sreelatha Melemadathil3
The aim of the study is to study the outcome of deceased donor kidney transplantation at the end of one year, the effect of cold ischaemia on the outcome of graft survival and the role of various induction agents in the prevention of acute rejection.
MATERIALS AND METHODS
A retrospective observational study of 30 deceased donor kidney transplant recipients was conducted. All patients received triple drug immunosuppressive treatment, i.e. tacrolimus, steroids and mycophenolate. Induction with either ATG or basiliximab was given to all recipients. The graft function was monitored serially with serum creatinine and routine urine examination. Graft biopsy was done in the event of graft dysfunction. Development of infection was confirmed by serological examination and cultures of various body fluids.
One year graft survival was 80% and patient survival was 83%. Delayed graft function was seen in 30% and acute rejection in 33%. Cold ischaemia was more than 6 hours in 23%. Induction was given to all patients and graft function was similar in both groups. 40% patients developed infection during the first year.
One year graft survival is 80% and patient survival is 83%. 40% patients developed infection.