Thambidurai Lasya1, Navin Gnanasekaran2, Venkata Sai3
BACKGROUND In 53 patients with non-obstructive renal disease, we compared the Doppler indices along with the corresponding histopathological findings.
METHODS Patients were subjected to Doppler ultrasound before biopsy was performed. Doppler indices, particularly the Resistivity Indices (RI) values were calculated. Biopsy was performed under ultrasound guidance and samples were sent for histopathological analysis. Histopathological Examination (HPE) findings were compared with recorded RI.
RESULTS RI values between 6-7 were seen in purely glomerular diseases with no interstitial involvement. RI values between 7.1-7.5 were seen in diseases which involved both the interstitium and glomeruli. Purely interstitial diseases showed RI values greater than 7.5.
CONCLUSIONS RI values calculated in patients with non-obstructive renal disease help in accurately classifying the type of renal disease. Doppler ultrasound can be a very useful adjunct to HPE in medical renal disease and help differentiate interstitial from glomerular diseases.