Sampathukumari S 1 , Thenmozhi G2 , Surya S 3
Labour is a natural process, which involves a series of regular and progressive uterine contractions causing effacement and dilatation of cervix leading to birth of the baby. In order to minimise the perinatal morbidity and mortality caused by the prolonged labour, several drugs have been tried to hasten the process of cervical dilatation and this study in one such exercise. AIM OF THE STUDY 1) To compare the efficacy of Hyoscine Bromide (IV) vs. Tramadol (IM) vs. Paracetamol (IV) on cervical dilatation in active labour. 2) To compare the duration of active phase of labour. 150 full-term women with gestational age 37-42 weeks, primi and multi singleton pregnancy with cephalic presentation in active labour were included in the study. Cases were divided into 3 groups - Group A: 50 cases of labour accelerated by Hyoscine Bromide 20 mg (IV), Group B: 50 cases of labour accelerated by Tramadol 50 mg (IM) and Group C: 50 cases of labour accelerated by Paracetamol 500 mg (IV). Mean duration of active phase of 1st stage of labour was 3 hrs. 8 mins. (primi) and 2 hrs. 3 mins. (multi) in Hyoscine Bromide group and 4 hrs. 8 mins. (primi) and 3 hrs. 5 mins. (multi) in Tramadol group and 4 hrs. 2 mins. (primi) and 2 hrs. 5 mins. (multi) in Paracetamol group. Mean rate of cervical dilatation was 1.5 cm/hr (primi) and 2.6 cm/hr (multi) in Hyoscine Bromide group, 1.2 cm/hr (primi) and 1.6 cm/hr (multi) in Tramadol group and 1.3 cm/hr (primi) and 1.6 cm/hr (multi) in the Paracetamol group. The difference between the groups A and B and A and C is significant (p=0.0001) and thus it is concluded that Hyoscine Bromide hastened the rate of cervical dilatation and reduced the duration of active phase of 1 st stage of labour. Divide the abstract into materials and methods, results and conclusion.