Abstract

A CLINICAL STUDY OF PSEUDOEXFOLIATION IN A TERTIARY EYE CARE CENTRE

Author(s): Pragna Palagani1, Shruti K. Nair2, K. Mohan Raj3

BACKGROUND
Pseudoexfoliation is characterised by the deposition of homogeneous grey white material, which is produced by the abnormal basement membrane of epithelial cells of trabecular meshwork, lens capsule or iris gets deposited in various ocular structures. The material is composed of protein core surrounded by glycosaminoglycans. Glaucoma is classically of the open angle and however angle closure can occur due to pupil block. Pupil block in pseudoexfoliation patients occur either due to zonular instability and subsequent anterior displacement of lens-iris diaphragm or due to posterior synechiae associated with a rigid non-dilating pupil.
It is a prospective study to find out the associated features in patients with pseudoexfoliation.
MATERIALS AND METHODS
The study was conducted in Medical College Hospital over a period of one year from October 2016 to September 2017; 68 patients with pseudoexfoliation were examined.
RESULTS
In our study, we found the incidence of pseudoexfoliation was higher in patients between 51 - 70 years of age. It was unilateral in 59% of cases. Intraocular pressure was raised in 22% of cases. Only 14% of cases had closed angle. Glaucomatous optic neuropathy was seen in 19% of cases.
CONCLUSION
The prevalence of pseudoexfoliation is higher in elderly age group. The incidence of glaucoma is higher than in normal population. The other associated features like trabecular pigmentation and nuclear cataract are also more common in patients who had pseudoexfoliation.